Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth

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Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth

BACKGROUND Exercise promotes metabolic remodeling in the heart, which is associated with physiological cardiac growth; however, it is not known whether or how physical activity-induced changes in cardiac metabolism cause myocardial remodeling. In this study, we tested whether exercise-mediated changes in cardiomyocyte glucose metabolism are important for physiological cardiac growth. METHODS ...

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Experience affects exercise-induced changes in catecholamines, glucose, and FFA.

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Arterial concentrations and net substrate exchange across the leg and splanchnic vascular bed were determined for glucose, lactate, pyruvate, and glycerol in healthy postabsorptive subjects at rest and during 40 min of exercise on a bicycle ergometer at work intensities of 400, 800, and 1200 kg-m/min. Rising arterial glucose levels and small decreases in plasma insulin concentrations were found...

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ژورنال

عنوان ژورنال: Circulation

سال: 2017

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.117.028274